منابع مشابه
Activities and quantities of lysosomal enzymes during mammary tumor regression.
The relation of lysosomal enzymes to mammary tumor regression was studied in the highly hormone-dependent MTW9 rat mammary carcinoma. Quantities of the enzymes were determined with the use of a histochemical modification of the single radial immunodiffusion method. Major findings were as follows, (a) Acid phosphatase, arylsulfatase, ßgalactosidase, and 0-glucuronidase significantly increased i...
متن کاملMammary tumor regression. V. Role of acid ribonuclease and cathepsin.
Studies have been made on the role of two hydrolases, acid RNase and cathepsin, in the regression of hormone-dependent rat mammary carcinomas. A burst of acid RNase activity as early as 6 hours after hormonal deprivation was followed by a significant increase in cathepsin activity that began 48 hours after hormone removal. The ratios of free to bound activities of these enzymes increased with t...
متن کاملIncrease of RNA synthesis during mammary tumor regression.
751 Increase of RNA Synthesis during Mammary Tumor Regression. Pietro M. Gullino, Yoon Sang Cho-Chung, Ilona Losonczy, and Flora H. Grantham. 758 Prolactin Receptors in Mammary Carcinoma Cells. Roger W. Turkington. 764 Strainand Age-dependent Transplacental Car cinogenesis by 1-Ethyl-1-nitrosourea in Inbred Strains of Mice. Bhalchandra A. Diwan and Hans Meier. 771 Macromolecular Synthesis follo...
متن کاملMammary tumor regression elicited by Wnt signaling inhibitor requires IGFBP5.
Wnt ligand-driven tumor growth is inhibited by the soluble Wnt inhibitor Fzd8CRD, but the mechanism through which this effect is mediated is unknown. In the MMTV-Wnt1 mouse model, regression of mammary tumors by Fzd8CRD treatment coincides with an acute and strong induction of insulin-like growth factor (IGF)-binding protein IGFBP5, an antagonist of IGF signaling that mediates involution of mam...
متن کاملTumor and Stem Cell Biology Mammary Tumor Regression Elicited by Wnt Signaling Inhibitor Requires IGFBP5
Wnt ligand–driven tumor growth is inhibited by the soluble Wnt inhibitor Fzd8CRD, but the mechanism through which this effect is mediated is unknown. In the MMTV-Wnt1 mouse model, regression of mammary tumors by Fzd8CRD treatment coincides with an acute and strong induction of insulin-like growth factor (IGF)– binding protein IGFBP5, an antagonist of IGF signaling that mediates involution of ma...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1973
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)43728-9